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"Drug boosts testosterone, reduces waist-hip ratio in diabetic men"

Medical Post

Source: Medical Post

Published: 28 Jun 2022

Category: Pharmaceutical

Rating: (1½ stars)

what they said (Hover the mouse cursor over underlined words for more info)

SAN DIEGO | Diabetic men with low testosterone levels could possibly find another advantage in taking rosiglitazone (Avandia), according to results of a preliminary study presented at the annual meeting of the Endocrine Society here.

The original article can be found at:

The original article can found in the Media Doctor archives.

how did it rate? (more information)

Criteria Rating
Total Score 2 of 9
Availability of Treatment Not Satisfactory (?)
Novelty of Treatment Not Satisfactory (?)
Disease Mongering Satisfactory (?)
Treatment Options Not Satisfactory (?)
Costs of Treatment Not Satisfactory (?)
Evidence Not Satisfactory (?)
Quantification of Benefits of Treatment Satisfactory (?)
Harms of Treatment Not Satisfactory (?)
Sources of Information Not Satisfactory (?)
Relies on Press Release Not Applicable
Quantification of Harms of Treatment Not Applicable

what we said (Hover the mouse cursor over underlined words for more info)

This story about the benefits of rosiglitazone for central obesity describes the potential benefits in terms of surrogates markers such as hemoglobin A1C, or body weight.

However, the clinical significance of the difference of 0.02 kg in waist-hip is not related to clinical health outcomes. According to the article, treatment with this drug can increase testosterone levels, decrease central obesity and possibly reduce the incidence of heart disease. There are a lot of numbers thrown about showing the effectiveness of the medication but there is no evidence presented of any clinical benefit. In fact, the drug could be associated with overall weigh gaint. Other or serious side effects of the drug are not even considered.

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